Dental Health Of Chıldren Wıth Lymphoma Anı) Medulloblastoma After Chemoradiotherapy

Betul Sevinir, Çiğdem Çubukçu Elbek
Uludag University Faculty of Medicine. Department of Pediatric Dental Bursa, Turkey
Uludag University Faculty of Medicine. Department of Pediatric Dental Bursa. Turkey

This study atms lo asses the side elfeets of ehemotherapy and radıoiherapy on demal health of ehildreu who were ireated for lymphoma and medulloblastoma. Thirty-tvvo easesagcd3-l9years(nıedian 8.8 yr) \vho had been ireated for lymphomas (m 16) and medulioblasloma (n:16) vvere inciuded in this study. The median follovv-up lime finom the cessalion of the Ihernpy were 1.1 yr and 2.7 yr respectively. The teeth vvere e\aminetl for dental caries! dft/DMFT). abnormalilies of tooth nunıber and looth form. Parameter ol earious leelh (d/D) \vas divided as inaetive (di/DY) and actîvc (da/Da). The radiographic dental e\aminatİon inciuded assessmenl of root nıaiformalioıis and prematüre apexiliea(ions. The dala was analy/ed vvith ANOVA ıısing SPSS< 13.0). The highest score of bot h DMFranddft tndices vvere obtained in deeayed teeth eomponenl (D/d) in both groups. İn medulioblasloma group stıbjects vvho vvere adminisıered crania! irrad talkın, had ınore actîvc caries (Dal and fillings (F) on theİr permaııenı teeth eompared lo the subjects w itli lymphomas tP < 0.05). The freıprency of the ahnomıaliıies ıvas higher in medulloblastoma patients (p > 0.05). Root malformatioıis and enamel opacities vvere found in the eases vvith medulloblastoma (P < 0.05). Children vvho diagnosed beforc 5 yi of age and had crania) irradiation. shovved more harsh elfeets of the therapy. Tvvo children willi medulloblastoma vvere exhibited mierodontia anıl one chüd had prematüre apcNİlicatton of (İrsi pernıanent molar (p>0.05). İn this study children vvith lymphomas and medulloblastoma should be eonsidered as high risk group lor dental caries. Regular dental health examinations prior (o therapy w ili deerease the actîvc earious teeth scores. Close monitoring of the dental health slatus w ilh the help ol' ihc dental health prolessional integrated in oticology team vvill prevent and stabilize the formalion ol caries lesions and dental abnormalilies during the courses.